Human liver disease is modeled in swine. Liver cells transplanted, forming ectopic livers that cured fatal disease.
Transplanted swine liver cells are engrafted into the lymph nodes, proliferated, and form ectopic mini-livers.
The engineering of allogeneic cells to be ‘hypoimmunogenic’, also referred to as ‘universal’, so that they evade a host's immune system would be transformative for regenerative medicine.
A unified model of aging and loss of regenerative potential is emerging that may ultimately be translated into new therapeutic approaches for establishing induced tissue regeneration and modulation of the...
Unraveling some of the molecular signaling that appears to be crucial for engrafted kidney tissue to grow.
Expands upon findings in mice that show human ectopic kidney tissues can be grown using the lymph node as a bioreactor.